Novel Nucleoside Analogues to Combat Emerging Diseases
Viral diseases are an ever-present threat to public health, a reality the COVID-19 pandemic made painfully clear. While effective antiviral treatments exist for chronic diseases …
Exploring Science, Nature and Culture
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Selected Projects
My current and past projects in research and life.
Total Synthesis of Complex Natural Products
Total synthesis stands as one of the most intellectually demanding and logistically challenging disciplines within organic chemistry. Unlike highly applied branches such as process …
Molecular Editing of Natural Products
Natural products serve as powerful templates for drug development. The biosynthesis of secondary metabolites demands significant energy from the organism, which suggests that these …
My latest thoughts
New Targets for Molecular Glues
Human proteasome data mining study expands the possibilites of protein degradation.
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Selective Nitrosation by Covalent Binder Strategy
A novel strategy for improving our understanding of, and ability to utilise, nitrosation as a post-translational modification.
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New Method for Skeletal Rearrangement Enhances the Organic Chemist's Toolbox
Acyl transposition in dihydrobenzofuranes describend by Richmond Sarpong in Science
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Deracemisation lead to enriched alpha Amino Aldehydes
Luo and coworkes from Tsinghua University report a novel method for deracemisation in JACS
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Novel Synthetic Approach for the Synthesis of Pyrroloiminoquinones
The total synthesis of aleutianamin was enabled by a new convergent coupling reaction.
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Computer aided Total Synthesis of 25 Picrotoxanes (Li, Shenvi)
Calculations optimise the total synthesis of natural products by addressing challenges in the 1,5 HAT key reaction.
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