New Method for Skeletal Rearrangement Enhances the Organic Chemist's Toolbox
Acyl transposition in dihydrobenzofuranes describend by Richmond Sarpong in Science
May 9, 2025
Deracemisation lead to enriched alpha Amino Aldehydes
Luo and coworkes from Tsinghua University report a novel method for deracemisation in JACS
Feb 12, 2025
Novel Synthetic Approach for the Synthesis of Pyrroloiminoquinones
The total synthesis of aleutianamin was enabled by a new convergent coupling reaction.
Feb 11, 2025
Computer aided Total Synthesis of 25 Picrotoxanes (Li, Shenvi)
Calculations optimise the total synthesis of natural products by addressing challenges in the 1,5 HAT key reaction.
Jan 24, 2025
Efficient Synthesis of Chiral ProTides through Copper Catalysis
A new study introduces a novel method for the stereoselective synthesis of chiral phosphates in ProTide nucleoside analogues.
Nov 13, 2024
Exploring Anti-Bredt Olefins as Reactive Intermediates
The access and the usage of anti-Bredt type olefins as intermediates are described in a new study in Science.
Nov 10, 2024
A Day in Nature: Hiking Ma On Shan Country Park
Going for a hike from Shatin to Ma On Shan, I discovered breathtaking views of Sai Kung in the heart of Ma On Shan Country Park.
Oct 13, 2024
Start of the 2024/2025 Hiking Season: Scenic views from Lion Rock
Finally, the weather cooled down, allowing me to climb Lion Rock, which connects Shatin and Kowloon.
Oct 5, 2024
Personal Review: International Symposium on Medicinal Chemistry
Synthesis of stasseriolide natural products and their analogues using a ring-closing alkyne metathesis by Alois Fürstner and his team.
Sep 10, 2024
Macrocycles can lock the Conformation of Drug Candidates and enhance their Activity
Macrocycles can improve the conformation, biological activity, selectivity, ADME properties, and target affinity of small-molecule drug candidates.
Sep 10, 2024