Posts

New Targets for Molecular Glues featured image

New Targets for Molecular Glues

Human proteasome data mining study expands the possibilites of protein degradation.

Selective Nitrosation by Covalent Binder Strategy featured image

Selective Nitrosation by Covalent Binder Strategy

A novel strategy for improving our understanding of, and ability to utilise, nitrosation as a post-translational modification.

New Method for Skeletal Rearrangement Enhances the Organic Chemist's Toolbox featured image

New Method for Skeletal Rearrangement Enhances the Organic Chemist's Toolbox

Acyl transposition in dihydrobenzofuranes describend by Richmond Sarpong in Science

Deracemisation lead to enriched alpha Amino Aldehydes featured image

Deracemisation lead to enriched alpha Amino Aldehydes

Luo and coworkes from Tsinghua University report a novel method for deracemisation in JACS

Novel Synthetic Approach for the Synthesis of Pyrroloiminoquinones featured image

Novel Synthetic Approach for the Synthesis of Pyrroloiminoquinones

The total synthesis of aleutianamin was enabled by a new convergent coupling reaction.

Computer aided Total Synthesis of 25 Picrotoxanes (Li, Shenvi) featured image

Computer aided Total Synthesis of 25 Picrotoxanes (Li, Shenvi)

Calculations optimise the total synthesis of natural products by addressing challenges in the 1,5 HAT key reaction.

Efficient Synthesis of Chiral ProTides through Copper Catalysis featured image

Efficient Synthesis of Chiral ProTides through Copper Catalysis

A new study introduces a novel method for the stereoselective synthesis of chiral phosphates in ProTide nucleoside analogues.

Exploring Anti-Bredt Olefins as Reactive Intermediates featured image

Exploring Anti-Bredt Olefins as Reactive Intermediates

The access and the usage of anti-Bredt type olefins as intermediates are described in a new study in Science.

A Day in Nature: Hiking Ma On Shan Country Park featured image

A Day in Nature: Hiking Ma On Shan Country Park

Going for a hike from Shatin to Ma On Shan, I discovered breathtaking views of Sai Kung in the heart of Ma On Shan Country Park.

Start of the 2024/2025 Hiking Season: Scenic views from Lion Rock featured image

Start of the 2024/2025 Hiking Season: Scenic views from Lion Rock

Finally, the weather cooled down, allowing me to climb Lion Rock, which connects Shatin and Kowloon.