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Structural Modifications Enhance Antibacterial Potency of Bacitracin featured image

Structural Modifications Enhance Antibacterial Potency of Bacitracin

Researchers modified the structure of the established antibiotic bacitracin, leading to a 256-fold increase in activity and potent inhibition of vancomycin-resistant strains.

Novel Synthesis Route to Platensilin and Analogues featured image

Novel Synthesis Route to Platensilin and Analogues

Researchers from Shandong University in China reported the total synthesis of platensilin and platensimycin, as well as the formal synthesis of platencin in JACS, using a …

Exploring Xiamen on a Short trip featured image

Exploring Xiamen on a Short trip

Xiamen is a coastal city in southeastern China's Fujian province. I enjoyed its cultural heritage, beautiful natural landscapes and relaxed atmosphere during my short trip.

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade featured image

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade

A radical cascade strategy to synthesize the complex marine natural product, Scabrolide A, is described in JACS by Pengfei Hu and coworkers.

Hiking in Tsing Yi featured image

Hiking in Tsing Yi

As the weather in Hong Kong becomes increasingly humid in late spring, hiking can become more challenging, but the island of Tsing Yi offers rewarding hiking options well-suited …

My Reading Tip of the Week: Efficacy of Remdesivir ProDrugs featured image

My Reading Tip of the Week: Efficacy of Remdesivir ProDrugs

The efficacy of triphosphate formation of remdesivir is dependent on ProTide substitution. Higher levels of triphosphate in the lung are observed with ProTide prodrugs.