Structural Modifications Enhance Antibacterial Potency of Bacitracin
Researchers modified the structure of the established antibiotic bacitracin, leading to a 256-fold increase in activity and potent inhibition of vancomycin-resistant strains.
Researchers modified the structure of the established antibiotic bacitracin, leading to a 256-fold increase in activity and potent inhibition of vancomycin-resistant strains.
Researchers from Shandong University in China reported the total synthesis of platensilin and platensimycin, as well as the formal synthesis of platencin in JACS, using a …
Xiamen is a coastal city in southeastern China's Fujian province. I enjoyed its cultural heritage, beautiful natural landscapes and relaxed atmosphere during my short trip.
A radical cascade strategy to synthesize the complex marine natural product, Scabrolide A, is described in JACS by Pengfei Hu and coworkers.
As the weather in Hong Kong becomes increasingly humid in late spring, hiking can become more challenging, but the island of Tsing Yi offers rewarding hiking options well-suited …
The efficacy of triphosphate formation of remdesivir is dependent on ProTide substitution. Higher levels of triphosphate in the lung are observed with ProTide prodrugs.