Copper Catalysis

Organic Chemistry

Practical access to trisubstituted Morita‐Baylis‐Hillman‐type products through copper‐catalyzed reductive aldol reactions of alkynones

AbstractWe report a convenient and diastereoselective copper‐catalyzed reductive alkynone aldol addition to aldehydes, with pinacolborane as stoichiometric reductant, that results …

avatar
Stephan Scheeff
•
Read more
Diastereo- and enantioselective construction of stereochemical arrays exploiting non-classical hydrogen bonding in enolborates featured image
Organic Chemistry

Diastereo- and enantioselective construction of stereochemical arrays exploiting non-classical hydrogen bonding in enolborates

We report a copper-catalyzed reductive aldol addition to aldehydes and ketones, with pinacolborane as stoichiometric reductant, that results in the generation of stereodefined …

matthew-li
•
Read more
Organic Chemistry

Copper-catalyzed reductive Ireland-Claisen rearrangements of propargylic acrylates and allylic allenoates

The copper-catalyzed reductive Ireland-Claisen rearrangement of propargylic acrylates led to 3,4-allenoic acids. The use of silanes or pinacolborane as stoichiometric reducing …

siyuan-guo
•
Read more