JACS

Selective Nitrosation by Covalent Binder Strategy featured image

Selective Nitrosation by Covalent Binder Strategy

A novel strategy for improving our understanding of, and ability to utilise, nitrosation as a post-translational modification.

Efficient Synthesis of Chiral ProTides through Copper Catalysis featured image

Efficient Synthesis of Chiral ProTides through Copper Catalysis

A new study introduces a novel method for the stereoselective synthesis of chiral phosphates in ProTide nucleoside analogues.

Synthesis of Quaternary Centres using Lithium Enolates in a Ru-catalysed Allylic substitution featured image

Synthesis of Quaternary Centres using Lithium Enolates in a Ru-catalysed Allylic substitution

The construction of quaternary centers via C-C bond formation is a significant challenge, but a new method reported in JACS, provides a promising approach to accessing these …

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade featured image

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade

A radical cascade strategy to synthesize the complex marine natural product, Scabrolide A, is described in JACS by Pengfei Hu and coworkers.