Publication of the Week

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade featured image

My Reading Tip of the Week: Total Synthesis of Scabrolide A by Radical Cascade

A radical cascade strategy to synthesize the complex marine natural product, Scabrolide A, is described in JACS by Pengfei Hu and coworkers.

My Reading Tip of the Week: Efficacy of Remdesivir ProDrugs featured image

My Reading Tip of the Week: Efficacy of Remdesivir ProDrugs

The efficacy of triphosphate formation of remdesivir is dependent on ProTide substitution. Higher levels of triphosphate in the lung are observed with ProTide prodrugs.