Computer aided Total Synthesis of 25 Picrotoxanes (Li, Shenvi)
Calculations optimise the total synthesis of natural products by addressing challenges in the 1,5 HAT key reaction.
Jan 24, 2025
Novel Synthesis Route to Platensilin and Analogues
Researchers from Shandong University in China reported the total synthesis of platensilin and platensimycin, as well as the formal synthesis of platencin in JACS, using a biomimetic approach that allowed the formation of all three natural products from a common precursor.
Jul 9, 2024